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Postdoctoral Position: integrative physiology


One postdoctoral position is available in the laboratory of Dr. Keith Nehrke at the University of Rochester Medical Center. The focus of the laboratory is on integrative physiology using C. elegans as a model system. One of the main goals of the project will be to determine how acid-base transport and pHi influence the cellular and trans-cellular signaling pathways that regulate metabolism and aging. In particular, we are looking for someone with a background in genetics to pursue a suppressor screen of the Na+/H+ exchanger isoform nhx-2(-) larval arrest deficit (Nehrke, 2003), as well as an epistasis analysis of cell signaling and pHi regulatory processes. At least a working knowledge of molecular biology is required. The project will provide in turn the opportunity to learn real-time imaging techniques for following electrolyte and calcium flux in live worms.

Rochester is a midsize Northeastern town on the shores of Lake Ontario, and with the beautiful Finger Lakes less than half-an-hour away, it’s a great place to live life and raise a family. The University of Rochester Medical Center is a premier research institute with two brand new medical research buildings and a robust academic atmosphere.

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Please send a CV, a statement of research goals, and contact information for references to:

Dr. Keith Nehrke
Department of Medicine, Nephrology Division
Box 675
University of Rochester Medical Center
575 Elmwood ave.
Rochester, NY 14620
Or E-mail the same to: Keith_Nehrke@urmc.rochester.edu