The nematode C. elegans is both genomically-defined
and genetically-tractable, and has emerged as a leading model
system for the study of integrative physiology. In fact, more
than 750 genes or ~4% of the worm genome encode proteins involved
in ATP-dependent, secondary active, and passive channel-mediated
transport processes suggesting that the electrical properties
of individual cells could be conserved across species. My laboratory
uses C. elegans as a model system to study
epithelial membrane transport through a variety of novel approaches
that are only possible in this well-characterized organism.
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